One of the leading cancer centers in the nation, UNC Lineberger Comprehensive Cancer Center is located in Chapel Hill, North Carolina. As one of only 40 National Cancer Institute-designated Icon indicating that a link will open an external site. comprehensive cancer centers, UNC Lineberger was rated as exceptional, the highest category, by the National Cancer Institute. The center brings together some of the most exceptional physicians and scientists in the country to investigate and improve the prevention, early detection and treatment of cancer.